PDRN New Concept Skin Treatment (韩国婴儿针)

by combining PDRN with Dermapen Treatment.

Non-invasive, no injection anti-ageing procedure that harnesses salmon DNA to repair and renew at the cellular level to achieve younger-looking skin.

PDRN molecules,derived from salmon DNA, have been long used for tissue-repair and anti-inflammatory properties.

It works to stimulate skin rejuvenation through engaging the right receptors responsible for anti-inflammation and promoting healing, and also activating the pathway to boost your skin’s recovery and resilience.

Scientific jargon aside,it truly works within your deeper skin layers to repair damaged DNA at the cellular level – in short, fighting the sign of ageing right at it’s roots.

Hence, it has been coined as  婴儿针 in South Korea and China where this treatment is immensely popular amongst ladies.

 

  • Step 1 :  Cleansing is applied on the skin for 5 minutes.
  • Step 2 :  Your aesthetician  then uses a dermapen to administer tiny amounts of PDRN under the skin.Treatments can vary from 20 minutes.
  • Step 3 :  Re-apply cleansing to treat area. 5 minutes.
  • Step 4 :  Apply face mask.
  • Result: Visible immediate result from day 1 onwards.
  • Downtime: No downtime, except for some slight redness
  • Treatment Duration: 30 minutes 
  • Discomfort: Minimum
  • Result: Less wrinkle and more radiance
  • Recommended number of treatments: Minimum of 3 with 10-14 days interval. Thereafter 6 monthly maintenance.

 

More about PDRN & Dermapen Treatment

  • Dark eye circles
  • Enlarged pores
  • Skin sagging
  • Enlarged pores
  • Dull skin
  • Wrinkles and fine lines
  • Acne scars
  • Stretch Marks
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References:

1. A Phase III, Randomized, Double-Blind, Matched-Pairs, Active-Controlled Clinical Trial and Preclinical Animal Study to Compare the Durability, Efficacy and Safety between Polynucleotide Filler and Hyaluronic Acid Filler in the Correction of Crow’s Feet: A New Concept of Regenerative Filler. Chang et al. J Korean Med Sci. 2014 Nov; 29(Suppl 3): S201–S209.

2. Polydeoxyribonucleotide Improves Peripheral Tissue Oxygenation and Accelerates Angiogenesis in Diabetic Foot Ulcers. Kim et al. Arch Plast Surg. 2017 Nov;44(6):482-489. doi: 10.5999/aps.2017.00801.

3. Polydeoxyribonucleotide Dermal Infiltration in Male Genital Lichen Sclerosus: Adjuvant Effects during Topical Therapy. Laino L, Suetti S, Sperduti I. Dermatol Res Pract. 2013;2013:654079. doi: 10.1155/2013/654079.

4. Novel Anti-Melanogenesis Properties of Polydeoxyribonucleotide, a Popular Wound Healing Booster. Noh TK, Chung BY, Kim SY, Lee MH, Kim MJ, Youn CS, Lee MW, Chang SE. Int J Mol Sci. 2016 Sep 1;17(9). pii: E1448. doi: 10.3390/ijms17091448.

5. Clinical evaluation of the trophic effect of polydeoxyribonucleotide (PDRN) in patients undergoing skin explants. A Pilot Study. Rubegni P, De Aloe G, Mazzatenta C, Cattarini L, Fimiani M. Curr Med Res Opin. 2001;17(2):128-31.

6. Evaluation of the efficacy of polydeoxyribonucleotides in the healing process of autologous skin graft donor sites: a pilot study. Valdatta L, Thione A, Mortarino C, Buoro M, Tuinder S. Curr Med Res Opin. 2004 Mar;20(3):403-8.

7. Therapeutic efficacy of autologous platelet-rich plasma and polydeoxyribonucleotide on female pattern hair loss. Lee SH, Zheng Z, Kang JS, Kim DY, Oh SH, Cho SB.Wound Repair Regen. 2015 Jan-Feb;23(1):30-6. doi: 10.1111/wrr.12250.

8. Pharmacological Activity and Clinical Use of PDRN. Francesco Squadrito, Alessandra Bitto, Natasha Irrera, Gabriele Pizzino, Giovanni Pallio, Letteria Minutoli, Domenica Altavilla. Front Pharmacol. 2017; 8: 224. Published online 2017 Apr 26. doi: 10.3389/fphar.2017.00224

9. Scar Prevention and Enhanced Wound Healing Induced by Polydeoxyribonucleotide in a Rat Incisional Wound-Healing Model. Jeong W, Yang CE, Roh TS, Kim JH, Lee JH, Lee WJ. Int J Mol Sci. 2017 Aug 3;18(8). pii: E1698. doi: 10.3390/ijms18081698.

10. Polydeoxyribonucleotides enhance the proliferation of human skin fibroblasts: involvement of A2 purinergic receptor subtypes. Thellung S, Florio T, Maragliano A, Cattarini G, Schettini G. Life Sci. 1999;64(18):1661-74.

11. Effect of polydeoxyribonucleotides on human fibroblasts in primary culture.Sini P1, Denti A, Cattarini G, Daglio M, Tira ME, Balduini C. Cell Biochem Funct. 1999 Jun;17(2):107-14.

12. Effect of DNA from salmon milt on human skin conditions. Hsu et al. International J of Cosmetic Science. 2010